Electron-catalyzed radical perfluoroalkylation of organic sulfides: the serendipitous use of the TMEDA/I2 complex as a radical initiatorElectronic supplementary information (ESI) available. See DOI: 10.1039/c7cy00236j

Radical initiation for the perfluoroalkylation reaction of sulfides has been performed using the complex [(TMEDA)I·I 3 ] and visible light. This methodology bypasses the use of metal(organo)catalysts where the complex [(TMEDA)I·I 3 ] acts as a good electron donor/reductant radical initiating agent....

Full description

Saved in:
Bibliographic Details
Main Authors Yerien, D. E, Barata-Vallejo, S, Camps, B, Cristófalo, A. E, Cano, M. E, Uhrig, M. L, Postigo, A
Format Journal Article
LanguageEnglish
Published 07.06.2017
Online AccessGet full text

Cover

More Information
Summary:Radical initiation for the perfluoroalkylation reaction of sulfides has been performed using the complex [(TMEDA)I·I 3 ] and visible light. This methodology bypasses the use of metal(organo)catalysts where the complex [(TMEDA)I·I 3 ] acts as a good electron donor/reductant radical initiating agent. Biologically relevant sulfides are easily substituted with R F moieties employing a mild and environmentally benign radical strategy starting from readily available R F I. The (TMEDA)I·I 3 complex as a new radical initiator for the perfluoroalkylation of RSH.
Bibliography:10.1039/c7cy00236j
Electronic supplementary information (ESI) available. See DOI
ISSN:2044-4753
2044-4761
DOI:10.1039/c7cy00236j