Folding induced supramolecular assembly into pH-responsive nanorods with a protein repellent shellElectronic supplementary information (ESI) available: Additional experimental data (TEM, fluorescence and 1H DOSY-NMR) as well as synthetic details and full analytical characterisation. See DOI: 10.1039/c7cc08127h

We report the synthesis of ABA′ triblock peptide-polysarcosine-peptide conjugates featuring two complementary phenylalanine-histidine pentapeptide strands A/A′. These sequences encode for antiparallel β-sheet formation into folded conjugates, which promote the self-assembly into polysarcosine-shield...

Full description

Saved in:
Bibliographic Details
Main Authors Otter, R, Klinker, K, Spitzer, D, Schinnerer, M, Barz, M, Besenius, P
Format Journal Article
LanguageEnglish
Published 04.01.2018
Online AccessGet full text

Cover

More Information
Summary:We report the synthesis of ABA′ triblock peptide-polysarcosine-peptide conjugates featuring two complementary phenylalanine-histidine pentapeptide strands A/A′. These sequences encode for antiparallel β-sheet formation into folded conjugates, which promote the self-assembly into polysarcosine-shielded core-shell nanorods. These do not cause aggregation of serum proteins in human blood plasma underlining an enhanced stability. ABA′ triblock peptide-polysarcosine-peptide conjugates fold into antiparallel β-sheets, which promotes the self-assembly into polysarcosine-shielded core-shell nanorods with protein repellent properties.
Bibliography:1
H DOSY-NMR) as well as synthetic details and full analytical characterisation. See DOI
10.1039/c7cc08127h
Electronic supplementary information (ESI) available: Additional experimental data (TEM, fluorescence and
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc08127h