FeCl3-Catalyzed synthesis of pyrrolo[1,2-a]quinoxaline derivatives from 1-(2-aminophenyl)pyrroles through annulation and cleavage of cyclic ethersElectronic supplementary information (ESI) available: Experimental procedures spectroscopic data and X-ray data. CCDC 1572973. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7cc07089f

• Main Authors: An, Zhenyu, Zhao, Lianbiao, Wu, Mingzhong, Ni, Jixiang, Qi, Zhenjie, Yu, Guiqin, Yan, Rulong
• Format: Journal Article
• Published: 19.10.2017
• ISSN: 1359-7345; 1364-548X
• DOI: 10.1039/c7cc07089f

A straightforward Fe-catalyzed method for the synthesis of pyrrolo[1,2- a ]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclic ethers, which includes functionalization of C(sp 3 )-H bonds and the construction of C-C and C-N bonds, has been developed. The features of this reaction are Fe catalysis, low-cost and readily accessible starting materials. Moreover, this procedure exhibits good functional group tolerance and a series of pyrrolo[1,2- a ]quinoxaline derivatives are obtained in moderate to good yields. A straightforward Fe-catalyzed method for the synthesis of pyrrolo[1,2- a ]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclic ethers, which includes functionalization of C(sp 3 )-H bonds and the construction of C-C and C-N bonds, has been developed.