An AIE-based bioprobe for differentiating the early and late stages of apoptosis mediated by H2O2Electronic supplementary information (ESI) available: The syntheses and characterization of TPE-Zn2BDPA, toxicity, cell apoptosis detection of Hep-G2 cell line. See DOI: 10.1039/c6tb01734g

A bioprobe, TPE-Zn 2 BDPA, with aggregation-induced emission characteristics was designed and synthesized to differentiate the early and late stages of apoptosis mediated by H 2 O 2 . TPE-Zn 2 BDPA does not respond to healthy cells, but it selectively lights up the membrane of apopotic cells in both...

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Bibliographic Details
Main Authors Leung, Anakin C. S, Zhao, Engui, Kwok, Ryan T. K, Lam, Jacky W. Y, Leung, Chris W. T, Deng, Haiqin, Tang, Ben Zhong
Format Journal Article
Published 17.08.2016
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Summary:A bioprobe, TPE-Zn 2 BDPA, with aggregation-induced emission characteristics was designed and synthesized to differentiate the early and late stages of apoptosis mediated by H 2 O 2 . TPE-Zn 2 BDPA does not respond to healthy cells, but it selectively lights up the membrane of apopotic cells in both stages with brighter fluorescence in the late apoptotic stage. A bioprobe, TPE-Zn 2 BDPA, with aggregation-induced emission characteristics was designed and synthesized to differentiate the early and late stages of apoptosis mediated by H 2 O 2 .
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BDPA, toxicity, cell apoptosis detection of Hep-G2 cell line. See DOI
10.1039/c6tb01734g
Electronic supplementary information (ESI) available: The syntheses and characterization of TPE-Zn
ISSN:2050-750X
2050-7518
DOI:10.1039/c6tb01734g