Discovery of aromadendrane anologues from the marine-derived fungus Scedosporium dehoogii F41-4 by NMR-guided isolationElectronic supplementary information (ESI) available: The NMR spectra data of compounds 1-9. See DOI: 10.1039/c6ra21142a

Eight closely biogenetically-related aromadendrane-type sesquiterpenoids, six of them new, scedogiines A-F ( 1-3 , 6-8 ), together with a new polyketide scedogiine G ( 9 ) were discovered from the culture broth of the marine-derived fungus Scedosporium dehoogii F41-4 by NMR-guided isolation. Their s...

Full description

Saved in:
Bibliographic Details
Main Authors Hu, Kun-Chao, Xu, Meng-Yang, Li, Hou-Jin, Yuan, Jie, Tang, Ge, Xu, Jun, Yang, De-Po, Lan, Wen-Jian
Format Journal Article
LanguageEnglish
Published 04.10.2016
Online AccessGet full text

Cover

More Information
Summary:Eight closely biogenetically-related aromadendrane-type sesquiterpenoids, six of them new, scedogiines A-F ( 1-3 , 6-8 ), together with a new polyketide scedogiine G ( 9 ) were discovered from the culture broth of the marine-derived fungus Scedosporium dehoogii F41-4 by NMR-guided isolation. Their structures were determined from extensive NMR and HR-ESI-MS data. The absolute configurations of the new sesquiterpenoids were elucidated by ECD calculation. Plausible biogenetic pathways of the aromadendrane analogues were postulated. Six new aromadendrane sesquiterpenoids and two known analogues, together with a new polyketide were discovered from the marine-derived fungus Scedosporium dehoogii by NMR-guided isolation. The biosynthetic pathways of sesquiterpenoids were proposed.
Bibliography:Electronic supplementary information (ESI) available: The NMR spectra data of compounds
10.1039/c6ra21142a
See DOI
1-9
ISSN:2046-2069
DOI:10.1039/c6ra21142a