Synthesis of [123I]-iodometomidate from a polymer-supported precursor with a large excluded volumeElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra00442c

We report on the synthesis of [ 123 I]-iodometomidate from a soluble polymer-supported precursor. The precursor was linked through a soluble polymer via a silyl linker polymer-supported precursor and released [ 123 I]-iodometomidate. The radiotracers were purified based on a combination of size-excl...

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Bibliographic Details
Main Authors Nakagawa, Chika, Toyama, Masahito, Takeuchi, Ryota, Takahashi, Takashi, Tanaka, Hiroshi
Format Journal Article
Published 29.01.2016
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Summary:We report on the synthesis of [ 123 I]-iodometomidate from a soluble polymer-supported precursor. The precursor was linked through a soluble polymer via a silyl linker polymer-supported precursor and released [ 123 I]-iodometomidate. The radiotracers were purified based on a combination of size-exclusive and normal-phase chromatography to provide [ 123 I]-iodometomidate in good quality. We report on the synthesis of [ 123 I]-iodometomidate from a soluble polymer-supported precursor with a large extent volume. The precursor enabled the synthesis of the [ 123 I]-iodometomidate with high quality without use of HPLC purification.
Bibliography:10.1039/c6ra00442c
Electronic supplementary information (ESI) available. See DOI
ISSN:2046-2069
DOI:10.1039/c6ra00442c