Highly solvatochromic and tunable fluorophores based on a 4,5-quinolimide scaffold: novel CDK5 probesThis manuscript is dedicated to Professor M. Teresa García-López on occasion of her retirement after a distinguished scientific career on Medicinal Chemistry.Electronic supplementary information (ESI) available: Experimental procedures, photophysical and calculation data, figures of titration and cell imaging of a quinolimide labelled CDK5 peptide, as well as, NMR spectra. See DOI: 10.1039/c6cc04
Novel 4,5-quinolimide-based fluorophores are more solvatochromic and red-shifted than known naphthalimide analogues. Conjugation of one of these fluorophores to a peptide derived from CDK5 kinase demonstrated its sensitivity for monitoring the interaction with its regulatory partner p25. Introductio...
Saved in:
Main Authors | , , , , , |
---|---|
Format | Journal Article |
Published |
26.07.2016
|
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!