Iodine catalysed intramolecular C(sp3)-H functionalization: synthesis of 2,5-disubstituted oxazoles from N-arylethylamidesElectronic supplementary information (ESI) available: Detailed experimental procedures and spectroscopic data. See DOI: 10.1039/c5ra13441b

Iodine catalyzed synthesis of 2,5-disubstituted oxazoles from N -arylethylamides through intramolecular C(sp 3 )-H functionalization under metal-free conditions is described. The method is tolerable to a wide range of substrates having a variety of functional groups with moderate to good yields of t...

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Bibliographic Details
Main Authors Samanta, Supravat, Donthiri, Ramachandra Reddy, Dinda, Milan, Adimurthy, Subbarayappa
Format Journal Article
LanguageEnglish
Published 05.08.2015
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Summary:Iodine catalyzed synthesis of 2,5-disubstituted oxazoles from N -arylethylamides through intramolecular C(sp 3 )-H functionalization under metal-free conditions is described. The method is tolerable to a wide range of substrates having a variety of functional groups with moderate to good yields of the products. Iodine catalyzed synthesis of 2,5-substituted oxazoles from N -arylethylamides through intramolecular C(sp 3 )-H functionalization under metal-free conditions is described.
Bibliography:10.1039/c5ra13441b
Electronic supplementary information (ESI) available: Detailed experimental procedures and spectroscopic data. See DOI
ISSN:2046-2069
DOI:10.1039/c5ra13441b