"Armed and disarmed" theory in the addition of an azide radical to glucalsElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ra00296f

In this report, "armed and disarmed" theory was used to explain the selectivity of azide radical addition to glucals. We discovered that "armed" glucals were prone to undergo a kinetic process. The torsional strains govern the selectivity. Meanwhile, "disarmed" glucals...

Full description

Saved in:
Bibliographic Details
Main Authors Wang, Wenjun, Yang, Zhongyue, Xu, Yun, Liu, Taibao, Song, Tianbang, Zhao, Yunyan, Xu, Xiufang, Zhao, Wei, Wang, Peng George
Format Journal Article
LanguageEnglish
Published 27.04.2015
Online AccessGet full text

Cover

More Information
Summary:In this report, "armed and disarmed" theory was used to explain the selectivity of azide radical addition to glucals. We discovered that "armed" glucals were prone to undergo a kinetic process. The torsional strains govern the selectivity. Meanwhile, "disarmed" glucals preferred thermodynamic radical addition. We also applied our method to synthesize a sialic acid containing trisaccharide. "Armed" glucals were prone to undergo kinetic process. The torsional strains govern the selectivity. Meanwhile, "disarmed" glucals preferred thermodynamic radical addition. A sialic acid containing trisaccharide was also synthesized by the method.
Bibliography:10.1039/c5ra00296f
Electronic supplementary information (ESI) available. See DOI
ISSN:2046-2069
DOI:10.1039/c5ra00296f