Solvent-free synthesis of pillar[6]arenesElectronic supplementary information (ESI) available: Experimental data and NMR spectra for all compounds. See DOI: 10.1039/c5gc01505g

An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H 2 SO 4 . The use of organic solvents for t...

Full description

Saved in:
Bibliographic Details
Main Authors Santra, S, Kopchuk, D. S, Kovalev, I. S, Zyryanov, G. V, Majee, A, Charushin, V. N, Chupakhin, O. N
Format Journal Article
Published 18.01.2016
Online AccessGet full text

Cover

More Information
Summary:An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H 2 SO 4 . The use of organic solvents for the extraction of products has also been avoided. Operational simplicity, compatibility with various 1,4-dialkoxybenzenes, non-chromatographic purification technique, high yields and mild reaction conditions are the notable advantages of this procedure. A large scale reaction demonstrated the practical applicability of this methodology. An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed.
Bibliography:Electronic supplementary information (ESI) available: Experimental data and NMR spectra for all compounds. See DOI
10.1039/c5gc01505g
ISSN:1463-9262
1463-9270
DOI:10.1039/c5gc01505g