Solvent-free synthesis of pillar[6]arenesElectronic supplementary information (ESI) available: Experimental data and NMR spectra for all compounds. See DOI: 10.1039/c5gc01505g
An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H 2 SO 4 . The use of organic solvents for t...
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Main Authors | , , , , , , |
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Format | Journal Article |
Published |
18.01.2016
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Online Access | Get full text |
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Summary: | An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H
2
SO
4
. The use of organic solvents for the extraction of products has also been avoided. Operational simplicity, compatibility with various 1,4-dialkoxybenzenes, non-chromatographic purification technique, high yields and mild reaction conditions are the notable advantages of this procedure. A large scale reaction demonstrated the practical applicability of this methodology.
An efficient solvent-free procedure for the synthesis of pillar[6]arenes has been developed. |
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Bibliography: | Electronic supplementary information (ESI) available: Experimental data and NMR spectra for all compounds. See DOI 10.1039/c5gc01505g |
ISSN: | 1463-9262 1463-9270 |
DOI: | 10.1039/c5gc01505g |