Reactions of allyl alcohols and boronic acids with trifluoromethanesulfonyl hypervalent iodonium ylide under copper-catalysisElectronic supplementary information (ESI) available: Synthetic methods and experimental data of the synthesized compounds. See DOI: 10.1039/c5dt02214b

Trifluoromethylsulfinyl and trifluoromethylthio groups are both important substituents for pharmaceuticals, agrochemicals and functional materials. We herein report the trifluoromethylthiolation of allyl alcohols 2 with trifluoromethanesulfonyl hypervalent iodonium ylide 1 under copper catalysis to...

Full description

Saved in:
Bibliographic Details
Main Authors Arimori, Sadayuki, Takada, Masahiro, Shibata, Norio
Format Journal Article
LanguageEnglish
Published 10.11.2015
Online AccessGet full text
ISSN1477-9226
1477-9234
DOI10.1039/c5dt02214b

Cover

More Information
Summary:Trifluoromethylsulfinyl and trifluoromethylthio groups are both important substituents for pharmaceuticals, agrochemicals and functional materials. We herein report the trifluoromethylthiolation of allyl alcohols 2 with trifluoromethanesulfonyl hypervalent iodonium ylide 1 under copper catalysis to provide trifluoromethylsulfinyl compounds 3 . Trifluoromethylthiolation of boronic acids 4 with 1 furnished trifluoromethylthio compounds 5 . Trifluoromethylsulfinyl 3 and trifluoromethylthio 5 compounds are independently obtained by using the sulfone-type reagent 1 under Cu catalysis.
Bibliography:Electronic supplementary information (ESI) available: Synthetic methods and experimental data of the synthesized compounds. See DOI
10.1039/c5dt02214b
ISSN:1477-9226
1477-9234
DOI:10.1039/c5dt02214b