Photo-click construction of a targetable and activatable two-photon probe imaging protease in apoptosisElectronic supplementary information (ESI) available. See DOI: 10.1039/c5cc09973k

A photo-click reaction was used as an efficient method to construct two-photon fluorescent probes bearing two functional peptides for targeting and for protease cleavage respectively. The activatable two-photon probe constructed by this method was applied to two-photon imaging of caspase-3 both in c...

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Bibliographic Details
Main Authors Zhou, Mi, Hu, Jing, Zheng, Mengmeng, Song, Qinhua, Li, Jinbo, Zhang, Yan
Format Journal Article
Published 28.01.2016
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Summary:A photo-click reaction was used as an efficient method to construct two-photon fluorescent probes bearing two functional peptides for targeting and for protease cleavage respectively. The activatable two-photon probe constructed by this method was applied to two-photon imaging of caspase-3 both in cellular apoptosis and in tumor tissue. Targetable and activatable two-photon probes constructed using photo-click chemistry were conducted in mitochondria, lysosome and apoptosis imaging.
Bibliography:10.1039/c5cc09973k
Electronic supplementary information (ESI) available. See DOI
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc09973k