Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylationElectronic supplementary information (ESI) available: Experimental procedures, characterization of data for all compounds. See DOI: 10.1039/c5cc02736e

Difluoromethylation of the activated X-H bond (X = N, O and S) and aliphatic thiols, and gem -difluorocyclopropenation of alkynes with difluorocarbene generated in situ from difluoromethylene phosphobetaine (Ph 3 P + CF 2 CO 2 − ) by decarboxylation occurred smoothly without the presence of any base...

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Bibliographic Details
Main Authors Deng, Xiao-Yun, Lin, Jin-Hong, Zheng, Jian, Xiao, Ji-Chang
Format Journal Article
LanguageEnglish
Published 12.05.2015
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Summary:Difluoromethylation of the activated X-H bond (X = N, O and S) and aliphatic thiols, and gem -difluorocyclopropenation of alkynes with difluorocarbene generated in situ from difluoromethylene phosphobetaine (Ph 3 P + CF 2 CO 2 − ) by decarboxylation occurred smoothly without the presence of any base or other additives. Difluoromethylation of the activated X-H bond and aliphatic thiols, and gem -difluorocyclopropenation of alkynes with difluorocarbene generated by decarboxylation are described.
Bibliography:Electronic supplementary information (ESI) available: Experimental procedures, characterization of data for all compounds. See DOI
10.1039/c5cc02736e
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc02736e