Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic aminesElectronic supplementary information (ESI) available: Experimental details, NMR spectra of all compounds, and X-ray crystallography of 7a and 11. CCDC 1040902 (7a) and 1040903 (11). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5cc00950b

A titanium-catalyzed cis -hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z -configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act a...

Full description

Saved in:
Bibliographic Details
Main Authors Sun, Renhong, Liu, Jun, Yang, Shuang, Chen, Ming, Sun, Ning, Chen, Haoyi, Xie, Xin, You, Xu, Li, Shi, Liu, Yuanhong
Format Journal Article
LanguageEnglish
Published 26.03.2015
Online AccessGet full text

Cover

More Information
Summary:A titanium-catalyzed cis -hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z -configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act as a real catalyst in this reaction. Titanium-catalyzed cis -hydroalumination of propargylic amines with Red-Al provides Z -configured allylic amines in good to excellent yields with high stereoselectivity.
Bibliography:CCDC
11
For ESI and crystallographic data in CIF or other electronic format see DOI
Electronic supplementary information (ESI) available: Experimental details, NMR spectra of all compounds, and X-ray crystallography of
and
10.1039/c5cc00950b
(
7a
1040903
1040902
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc00950b