APTEC: aptamer-tethered enzyme capture as a novel rapid diagnostic test for malariaElectronic supplementary information (ESI) available. See DOI: 10.1039/c5cc00438a

We report the rapid diagnosis of malaria by aptamer-tethered enzyme capture (APTEC) whereby an aptamer captures biomarker Plasmodium falciparum lactate dehydrogenase ( Pf LDH) then activity is measured colorimetrically. The robust test was sensitive (limit of detection = 4.9 ng mL −1 ) and could rel...

Full description

Saved in:
Bibliographic Details
Main Authors Dirkzwager, Roderick M, Kinghorn, Andrew B, Richards, Jack S, Tanner, Julian A
Format Journal Article
LanguageEnglish
Published 03.03.2015
Online AccessGet full text

Cover

More Information
Summary:We report the rapid diagnosis of malaria by aptamer-tethered enzyme capture (APTEC) whereby an aptamer captures biomarker Plasmodium falciparum lactate dehydrogenase ( Pf LDH) then activity is measured colorimetrically. The robust test was sensitive (limit of detection = 4.9 ng mL −1 ) and could reliably diagnose malaria in clinical blood samples. APTEC: aptamer-tethered enzyme capture as a novel rapid diagnostic test for malaria.
Bibliography:Electronic supplementary information (ESI) available. See DOI
10.1039/c5cc00438a
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc00438a