A novel phthalazine based highly selective chromogenic and fluorogenic chemosensor for Co2+ in semi-aqueous medium: application in cancer cell imagingElectronic supplementary information (ESI) available. See DOI: 10.1039/c4pp00358f
A new phthalazine based chemosensor 3 was developed for the highly selective and sensitive detection of Co 2+ in the mixed solvent system, CH 3 CN-H 2 O (1 : 1, v/v). In the presence of Co 2+ , the colour of the solution 3 changed from yellow to green; the absorption maxima of 3 was red-shifted from...
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| Main Authors | , , , , , , , , , |
|---|---|
| Format | Journal Article |
| Language | English |
| Published |
04.02.2015
|
| Online Access | Get full text |
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| Summary: | A new phthalazine based chemosensor
3
was developed for the highly selective and sensitive detection of Co
2+
in the mixed solvent system, CH
3
CN-H
2
O (1 : 1, v/v). In the presence of Co
2+
, the colour of the solution
3
changed from yellow to green; the absorption maxima of
3
was red-shifted from 383 nm to 435 nm, and the fluorescence of
3
at 550 nm was significantly enhanced. The sensor
3
showed a detection limit down to 25 nM by forming a complex species with Co
2+
in 1 : 1 stoichiometry. Furthermore, by means of confocal laser scanning microscopy experiments, it has demonstrated that it can be used as a fluorescent probe for monitoring Co
2+
in living cells.
A new phthalazine based chemosensor
3
was developed for the detection of Co
2+
. |
|---|---|
| Bibliography: | 10.1039/c4pp00358f Electronic supplementary information (ESI) available. See DOI |
| ISSN: | 1474-905X 1474-9092 |
| DOI: | 10.1039/c4pp00358f |