A highly selective sulfinate ester probe for thiol bioimagingElectronic supplementary information (ESI) available: Preparative procedures, characterization data, assay protocols and spectral data. See DOI: 10.1039/c4cc05462h

We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed. The sulfina...

Full description

Saved in:
Bibliographic Details
Main Authors Malwal, Satish R, Labade, Ajay, Andhalkar, Abhijeet S, Sengupta, Kundan, Chakrapani, Harinath
Format Journal Article
LanguageEnglish
Published 04.09.2014
Online AccessGet full text

Cover

Abstract We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed. The sulfinate ester functional group is found to be highly selective to cleavage by a thiol.
AbstractList We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed. The sulfinate ester functional group is found to be highly selective to cleavage by a thiol.
Author Andhalkar, Abhijeet S
Chakrapani, Harinath
Labade, Ajay
Malwal, Satish R
Sengupta, Kundan
AuthorAffiliation Indian Institute of Science Education and Research Pune
AuthorAffiliation_xml – name: Indian Institute of Science Education and Research Pune
Author_xml – sequence: 1
  givenname: Satish R
  surname: Malwal
  fullname: Malwal, Satish R
– sequence: 2
  givenname: Ajay
  surname: Labade
  fullname: Labade, Ajay
– sequence: 3
  givenname: Abhijeet S
  surname: Andhalkar
  fullname: Andhalkar, Abhijeet S
– sequence: 4
  givenname: Kundan
  surname: Sengupta
  fullname: Sengupta, Kundan
– sequence: 5
  givenname: Harinath
  surname: Chakrapani
  fullname: Chakrapani, Harinath
BookMark eNqFkMFKw0AQhhepYKtevAvjTaGpiUlq21vRij0p1IO3MtlMkpXt7rK7LcSn9VHcVMGDoHOZYeb752dmwHpKK2LsLIlHSZxOr3nGeZxn45vmgPWTdJxFeTZ57XV1Po1u0yw_YgPn3uIQST7ps485NKJuZAuOJHEvdgRuKyuh0BOQ82TBWF0QVNqCb4SWUAgtNlgLVS86idVK8CAyRtKGlEfbglAB36AXWsHlYrW8AtyhkFhImsGzJYMW915hN6dya8kNgTehy4OjeP9SluhxCOgcth3oNdfSAaoSnOmMUe6REayI4P5pOYPffzhhhxVKR6ff-ZidPyxe7h4j6_ja2HCIbdc_ePr__OKv-dqUVfoJIOKBZQ
ContentType Journal Article
DOI 10.1039/c4cc05462h
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
EISSN 1364-548X
EndPage 11535
ExternalDocumentID c4cc05462h
ID FETCH-rsc_primary_c4cc05462h3
ISSN 1359-7345
IngestDate Thu May 19 04:18:02 EDT 2016
Sat Jun 01 02:30:43 EDT 2019
IsPeerReviewed true
IsScholarly true
Issue 78
Language English
LinkModel OpenURL
MergedId FETCHMERGED-rsc_primary_c4cc05462h3
Notes 10.1039/c4cc05462h
Electronic supplementary information (ESI) available: Preparative procedures, characterization data, assay protocols and spectral data. See DOI
PageCount 3
ParticipantIDs rsc_primary_c4cc05462h
PublicationCentury 2000
PublicationDate 20140904
PublicationDateYYYYMMDD 2014-09-04
PublicationDate_xml – month: 9
  year: 2014
  text: 20140904
  day: 4
PublicationDecade 2010
PublicationYear 2014
References_xml – issn: 1997
  publication-title: Chiral Sulfur Reagents: Applications in Asymmetric and Stereoselective Synthesis
  doi: Mikolajczyk Drabowicz Kielbasinski
SSID ssj0000158
Score 4.3453746
Snippet We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at...
SourceID rsc
SourceType Enrichment Source
Publisher
StartPage 11533
Title A highly selective sulfinate ester probe for thiol bioimagingElectronic supplementary information (ESI) available: Preparative procedures, characterization data, assay protocols and spectral data. See DOI: 10.1039/c4cc05462h
Volume 5
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ3fb9MwEMet0j3ACxo_JjY2dA88gLIUtvxq9xaNohU2QFqR-lbZibNlhLRKGtD4X5H4U7izUyeDIAEvUWs7UWR_ZJ-du-8x9jSKhjwOEs9OPKk2KL5NsnU2d6NkiMtV8lJFyJ29808-um9m3qzX-97yWqpWYhB964wr-Z9RxTIcV4qS_YeRNQ_FAvyN44tXHGG8_tUYhxapDWfXVqmy2ZATUFllSZqjAWkpCQTyvxKy9iVMF5kl0kX6WWUmGjcJcEpK7andyAuKAzQRjWR_js8ndHTAv_A0ozgrOkP4UEijGa6WwLgq9HwTGQFoHd9pkQuqchEtS35NjVcLZE8rQ6swT1IIoEYDnLek9er9RB1SqDh9EimN3ChCg88_NOfWZzz7qtIUWOdcCTKZj1WnXNQywuFV4xwU5vElzz5pT_JQXKZX9B2-ST8m84tqqV_yLcXF5O2TkANXuXq5rcnbQcgCR8tTDmRd5rs27spm7Rnfa4GtEwjV0_cBWb8tW4D-e50LTWcX3BTubipvsY3DYOR5fbYRjqeT05a-mUoga158rZ_rjF40d6PVU6yz0SirZ7rJ7tbbFQg1e_dYT-b32e3jdZbAB-xHCJpBMAyCYRAUg6AYBIQKFIPQxSDcYBBaDMIzJPA5GP6OoEUfNPTtw6_sAWG1D4o8MOQBkgdr8lSTASB5gOQdwe_98pDtvR5Pj09s7J35UmuzzJtqZ4v180UuHzEIkjhxuYhc4eN2W3g88kfSd4QIHH-IG6BtttX9jG22010xX8bJzp_ueszuNHjusv6qqOQemq4r8aQG4Cc6rKWU
link.rule.ids 315,786,790,27955,27956
linkProvider Royal Society of Chemistry
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+highly+selective+sulfinate+ester+probe+for+thiol+bioimagingElectronic+supplementary+information+%28ESI%29+available%3A+Preparative+procedures%2C+characterization+data%2C+assay+protocols+and+spectral+data.+See+DOI%3A+10.1039%2Fc4cc05462h&rft.au=Malwal%2C+Satish+R&rft.au=Labade%2C+Ajay&rft.au=Andhalkar%2C+Abhijeet+S&rft.au=Sengupta%2C+Kundan&rft.date=2014-09-04&rft.issn=1359-7345&rft.eissn=1364-548X&rft.volume=5&rft.issue=78&rft.spage=11533&rft.epage=11535&rft_id=info:doi/10.1039%2Fc4cc05462h&rft.externalDocID=c4cc05462h
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1359-7345&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1359-7345&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1359-7345&client=summon