A highly selective sulfinate ester probe for thiol bioimagingElectronic supplementary information (ESI) available: Preparative procedures, characterization data, assay protocols and spectral data. See DOI: 10.1039/c4cc05462h
We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed. The sulfina...
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Main Authors | , , , , |
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Format | Journal Article |
Language | English |
Published |
04.09.2014
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Online Access | Get full text |
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Summary: | We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed.
The sulfinate ester functional group is found to be highly selective to cleavage by a thiol. |
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Bibliography: | 10.1039/c4cc05462h Electronic supplementary information (ESI) available: Preparative procedures, characterization data, assay protocols and spectral data. See DOI |
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c4cc05462h |