Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA displayElectronic supplementary information (ESI) available: Library construction, in vitro selection, binding assay, circular dichroism (CD) and peptide structure prediction. See DOI: 10.1039/c4cc00799a
Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by in vitro selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecula...
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Main Authors | , , |
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Format | Journal Article |
Language | English |
Published |
29.04.2014
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Online Access | Get full text |
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Summary: | Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by
in vitro
selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecular recognition.
Double disulphide-bridged loops of peptide aptamer are indispensable for the amino group recognition. |
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Bibliography: | 10.1039/c4cc00799a selection, binding assay, circular dichroism (CD) and peptide structure prediction. See DOI Electronic supplementary information (ESI) available: Library construction in vitro |
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c4cc00799a |