Pd(0)-catalyzed benzylic arylation-oxidation of 4-methylquinazolines via sp3 C-H activation under air conditionsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ob41488d

An efficient and selective Pd(0)-catalyzed sp 3 C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the...

Full description

Saved in:
Bibliographic Details
Main Authors Zhao, Dan, Zhu, Min-Xue, Wang, Yue, Shen, Qi, Li, Jian-Xin
Format Journal Article
LanguageEnglish
Published 07.10.2013
Online AccessGet full text

Cover

More Information
Summary:An efficient and selective Pd(0)-catalyzed sp 3 C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the sole oxidant. An efficient and selective Pd(0)-catalyzed sp 3 C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines.
Bibliography:10.1039/c3ob41488d
Electronic supplementary information (ESI) available. See DOI
ISSN:1477-0520
1477-0539
DOI:10.1039/c3ob41488d