Synthesis and spectroscopic properties of fluorescent 5-benzimidazolyl-2′-deoxyuridines 5-fdU probes obtained from o-phenylenediamine derivativesElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ob27519a

Fluorescent nucleosides (dU bmz ) with desirable fluorescence quantum yield ( Φ ) are synthesized from almost non-fluorescent 5-fdU and o -phenylenediamine derivatives. The fluorescence of these nucleosides is quite sensitive to pH and organic solvents. 4-Methoxybenzene-1,2-diamine was used for the...

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Main Authors Guo, Pu, Xu, Xiaowei, Qiu, Xiaoyu, Zhou, Yimin, Yan, Shengyong, Wang, Changcheng, Lu, Chunjiang, Ma, Wen, Weng, Xiaocheng, Zhang, Xianzheng, Zhou, Xiang
Format Journal Article
LanguageEnglish
Published 13.02.2013
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Summary:Fluorescent nucleosides (dU bmz ) with desirable fluorescence quantum yield ( Φ ) are synthesized from almost non-fluorescent 5-fdU and o -phenylenediamine derivatives. The fluorescence of these nucleosides is quite sensitive to pH and organic solvents. 4-Methoxybenzene-1,2-diamine was used for the detection of 5-fdU among natural nucleosides. o -Phenylenediamine was used for detecting 5-fdU among natural nucleosides to produce fluorescent nucleosides which are sensitive to pH and solvents.
Bibliography:10.1039/c3ob27519a
Electronic supplementary information (ESI) available. See DOI
ISSN:1477-0520
1477-0539
DOI:10.1039/c3ob27519a