In silico evolution of guiding track designs for molecular shuttles powered by kinesin motorsElectronic supplementary information (ESI) available: Description of the evolutionary algorithm employed in this research. Supplementary Figures showing the variability of results from evolutionary runs (Fig. S3-S6). See DOI: 10.1039/c3lc41103f

Molecular shuttles powered by kinesin motors require guiding tracks to perform specific tasks in nanoscale devices. Here, using our simulation of molecular shuttle movements, we describe an in silico evolutionary design method that makes it possible to automatically design the guiding tracks in acco...

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Bibliographic Details
Main Authors Sunagawa, Takuya, Tanahashi, Akihito, Downs, Matthew E, Hess, Henry, Nitta, Takahiro
Format Journal Article
LanguageEnglish
Published 18.06.2013
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Summary:Molecular shuttles powered by kinesin motors require guiding tracks to perform specific tasks in nanoscale devices. Here, using our simulation of molecular shuttle movements, we describe an in silico evolutionary design method that makes it possible to automatically design the guiding tracks in accordance with their functions defined by designers. With this design method, we designed two types of pre-existing guiding track modules with improved performances, as well as one with a novel function. A design method inspired by biological evolution enabled automated designs of mechanical nanodevices powered by kinesin motors.
Bibliography:Electronic supplementary information (ESI) available: Description of the evolutionary algorithm employed in this research. Supplementary Figures showing the variability of results from evolutionary runs (Fig. S3-S6). See DOI
10.1039/c3lc41103f
ISSN:1473-0197
1473-0189
DOI:10.1039/c3lc41103f