The potential of methylsiloxanes as solvents for synthetic chemistry applicationsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3gc42036a

• Main Authors: Ab Rani, Mohd Azri, Borduas, Nadine, Colquhoun, Victoria, Hanley, Robert, Johnson, Henry, Larger, Solène, Lickiss, Paul D, Llopis-Mestre, Veronica, Luu, Selina, Mogstad, Martin, Oczipka, Philipp, Sherwood, James R, Welton, Tom, Xing, Jun-Yi
• Format: Journal Article
• Language: English
• Published: 24.02.2014
• ISSN: 1463-9262; 1463-9270
• DOI: 10.1039/c3gc42036a

The potential use of volatile methylsiloxanes (VMSs) as solvents for chemicals synthesis has been explored. Assessment of the environmental impact of these VMS solvents is made and found to be significantly lower than those of the non-polar organic solvents that they have the potential to replace. The polarities of the VMSs, as expressed by empirical polarity measurements, and miscibilities with other liquids are found to be similar to those of alkane solvents. Finally, some uses of VMSs as solvents for both organic and inorganic transformations are described. The VMSs provide environmentally more sustainable (greener) alternatives to the nonpolar solvents that they have the potential to replace. The potential use of volatile methylsiloxanes (VMSs) as solvents for chemicals synthesis has been explored.