A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphismsElectronic supplementary information (ESI) available: Synthesis and characterization of the FNPs, the SNP assay procedure and comparison of the proposed assay with other SNP assays. See DOI: 10.1039/c3cc43281e

A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction. A simple and...

Full description

Saved in:
Bibliographic Details
Main Authors Shen, Wei, Lim, Cai Le, Gao, Zhiqiang
Format Journal Article
LanguageEnglish
Published 15.08.2013
Online AccessGet full text

Cover

More Information
Summary:A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction. A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes for highly sensitive and selective single-nucleotide polymorphism genotyping.
Bibliography:10.1039/c3cc43281e
Electronic supplementary information (ESI) available: Synthesis and characterization of the FNPs, the SNP assay procedure and comparison of the proposed assay with other SNP assays. See DOI
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc43281e