Syntheses of ()-pelletierine and ()-homopipecolic acidElectronic supplementary information (ESI) available: Experimental procedure, all 1H, 13C NMR spectra and assignment for all compounds, and HPLC chromatograms of (+)-3, (+)-6 and (+)-9, and crystallographic data of (+)-2-tartrate salt in CIF format. CCDC 855622. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c2ob06984a

Enantiomeric syntheses of ()-homopipecolic acid and ()-pelletierine have been achieved by chiral resolution of tropanol followed by BaeyerVilliger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. Enantiomeric syntheses of ()-homopipecolic acid an...

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Bibliographic Details
Main Authors Chiou, Wen-Hua, Chen, Guei-Tang, Kao, Chien-Lun, Gao, Yu-Kai
Format Journal Article
LanguageEnglish
Published 07.04.2012
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Summary:Enantiomeric syntheses of ()-homopipecolic acid and ()-pelletierine have been achieved by chiral resolution of tropanol followed by BaeyerVilliger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. Enantiomeric syntheses of ()-homopipecolic acid and ()-pelletierine have been achieved by chiral resolution of tropanol and BaeyerVilliger oxidation.
Bibliography:13
Electronic supplementary information (ESI) available: Experimental procedure, all
tartrate salt in CIF format. CCDC
and crystallographic data of (+)-
H
and (+)-
855622
1
For ESI and crystallographic data in CIF or other electronic format see DOI
2
3
10.1039/c2ob06984a
(+)-
6
9
C NMR spectra and assignment for all compounds, and HPLC chromatograms of (+)-
ISSN:1477-0520
1477-0539
DOI:10.1039/c2ob06984a