A microfluidic-based frequency-multiplexing impedance sensor (FMIS)Electronic Supplementary Information (ESI) available: See DOI: 10.1039/c2lc40236j/These authors contributed equally to this work

We present a novel technology for the simultaneous and simple impedimetric screening of multiple microfluidic channels with only one electrode pair. We have exploited the frequency dimension to distinguish between up to three channels. Each 'sub-sensor' possesses its corresponding measurem...

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Bibliographic Details
Main Authors Meissner, Robert, Joris, Pierre, Eker, Bilge, Bertsch, Arnaud, Renaud, Philippe
Format Journal Article
LanguageEnglish
Published 03.07.2012
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Summary:We present a novel technology for the simultaneous and simple impedimetric screening of multiple microfluidic channels with only one electrode pair. We have exploited the frequency dimension to distinguish between up to three channels. Each 'sub-sensor' possesses its corresponding measurement frequency where the sample-specific dielectric properties can be probed. We have shown the validity of our frequency-multiplexing impedance sensor (FMIS) by comparison with conventional 'single sensors'. Our highly sensitive FMIS was proven suitable for life science applications through usage as a cell-based toxicology platform. We are confident that our technology might find great utility in parallelized cell-based analysis systems as well as in biomedical devices where size limitations and spatially distributed probing are important parameters. We present a novel technology for the simultaneous and simple impedimetric screening of multiple microfluidic channels with only one electrode pair.
Bibliography:These authors contributed equally to this work.
Electronic Supplementary Information (ESI) available: See DOI
10.1039/c2lc40236j
ISSN:1473-0197
1473-0189
DOI:10.1039/c2lc40236j