Developing asymmetric iron and ruthenium-based cyclone complexes; complex factors influence the asymmetric induction in the transfer hydrogenation of ketonesElectronic supplementary information (ESI) available: Experimental details, NMR spectra. See DOI: 10.1039/c1ob06010d

The preparation of a range of asymmetric iron and ruthenium-cyclone complexes, and their application to the asymmetric reduction of a ketone, are described. The enantioselectivity of ketone reduction is influenced by a single chiral centre in the catalyst, as well as by the planar chirality in the c...

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Bibliographic Details
Main Authors Hopewell, Jonathan P, Martins, José E. D, Johnson, Tarn C, Godfrey, Jamie, Wills, Martin
Format Journal Article
LanguageEnglish
Published 07.01.2012
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Summary:The preparation of a range of asymmetric iron and ruthenium-cyclone complexes, and their application to the asymmetric reduction of a ketone, are described. The enantioselectivity of ketone reduction is influenced by a single chiral centre in the catalyst, as well as by the planar chirality in the catalyst. This represents the first example of asymmetric ketone reduction using an iron cyclone catalyst. The preparation of a range of asymmetric iron and ruthenium-cyclone complexes, and their application to the asymmetric reduction of a ketone, are described.
Bibliography:Electronic supplementary information (ESI) available: Experimental details, NMR spectra. See DOI
10.1039/c1ob06010d
ISSN:1477-0520
1477-0539
DOI:10.1039/c1ob06010d