De novo synthesis and lectin binding studies of unsaturated carba-pyranosesElectronic supplementary information (ESI) available: Synthetic procedures, NMR spectra and representative SPR binding sensorgrams. See DOI: 10.1039/c003597a

Starting from branched para -benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surfa...

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Main Authors Leermann, Timo, Block, Oliver, Podeschwa, Michael A. L, Pfüller, Uwe, Altenbach, Hans-Josef
Format Journal Article
LanguageEnglish
Published 07.09.2010
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Summary:Starting from branched para -benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy. Galactose analogues were synthesized from branched para -benzoquinones and their potential to act as competitive inhibitors in lectin-carbohydrate interactions was investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy.
Bibliography:Electronic supplementary information (ESI) available: Synthetic procedures, NMR spectra and representative SPR binding sensorgrams. See DOI
10.1039/c003597a
ISSN:1477-0520
1477-0539
DOI:10.1039/c003597a