Artificial, switchable K+-gated ion channels based on flow-through titania-nanotube arraysElectronic supplementary information (ESI) available: Additional experimental data. See DOI: 10.1039/b925961a

In the present work, we demonstrated a novel type of artificial K + -gated ion channels based on titania nanotubes loaded with Au nanoparticles and G-rich DNA composite structure. K + promoted conformational change of G-rich DNA from flexible chain to rigid quadruplex, which provided a blocking effe...

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Bibliographic Details
Main Authors Zhu, Bin, Li, Jingjian, Chen, Qingwei, Cao, Rui-Guo, Li, Jianming, Xu, Dongsheng
Format Journal Article
LanguageEnglish
Published 17.08.2010
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Summary:In the present work, we demonstrated a novel type of artificial K + -gated ion channels based on titania nanotubes loaded with Au nanoparticles and G-rich DNA composite structure. K + promoted conformational change of G-rich DNA from flexible chain to rigid quadruplex, which provided a blocking effect for the transport of anions such as Fe(CN) 6 4− and other molecules through the channels in TiO 2 nanotubes. This fabricated permselective membrane using K + as a trigger may set light to the field of biosensing, drug-release, ion exchange membrane and so on. K + -gated ion channels based on G-rich DNA modified titania nanotube-Au nanoparticle films were demonstrated, which had both controllability and selective permeability.
Bibliography:Electronic supplementary information (ESI) available: Additional experimental data. See DOI: 10.1039/b925961a
ISSN:1463-9076
1463-9084
DOI:10.1039/b925961a