Artificial, switchable K+-gated ion channels based on flow-through titania-nanotube arraysElectronic supplementary information (ESI) available: Additional experimental data. See DOI: 10.1039/b925961a
In the present work, we demonstrated a novel type of artificial K + -gated ion channels based on titania nanotubes loaded with Au nanoparticles and G-rich DNA composite structure. K + promoted conformational change of G-rich DNA from flexible chain to rigid quadruplex, which provided a blocking effe...
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Main Authors | , , , , , |
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Format | Journal Article |
Language | English |
Published |
17.08.2010
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Online Access | Get full text |
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Summary: | In the present work, we demonstrated a novel type of artificial K
+
-gated ion channels based on titania nanotubes loaded with Au nanoparticles and G-rich DNA composite structure. K
+
promoted conformational change of G-rich DNA from flexible chain to rigid quadruplex, which provided a blocking effect for the transport of anions such as Fe(CN)
6
4−
and other molecules through the channels in TiO
2
nanotubes. This fabricated permselective membrane using K
+
as a trigger may set light to the field of biosensing, drug-release, ion exchange membrane and so on.
K
+
-gated ion channels based on G-rich DNA modified titania nanotube-Au nanoparticle films were demonstrated, which had both controllability and selective permeability. |
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Bibliography: | Electronic supplementary information (ESI) available: Additional experimental data. See DOI: 10.1039/b925961a |
ISSN: | 1463-9076 1463-9084 |
DOI: | 10.1039/b925961a |