Clinical outcomes of adult patients hospitalized with covid-19 after vaccination
Vaccination remains the most effective way to prevent COVID-19. The aim of the present study was to assess the incidence of COVID-19 hospitalizations after vaccination, as well as the effect of prior vaccination on hospitalization outcomes among patients with COVID-19. We analyzed and compared all c...
Saved in:
Published in | Tropical medicine and infectious disease Vol. 6; no. 4; pp. 1 - 6 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Published |
Basel, Switzerland
MDPI
01.12.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Vaccination remains the most effective way to prevent COVID-19. The aim of the present study was to assess the incidence of COVID-19 hospitalizations after vaccination, as well as the effect of prior vaccination on hospitalization outcomes among patients with COVID-19. We analyzed and compared all consecutive patients, with or without prior vaccination, who were admitted to our hospital network due to COVID-19 from January to April 2021. Our primary outcome was to identify and describe cases of COVID-19 hospitalized after vaccination. We also utilized a multivariate logistic regression model to investigate the association of previous vaccination with hospitalization outcomes. We identified 915 consecutive patients hospitalized due to COVID-19 with 91/915 (10%) previously vaccinated with at least one dose of a COVID-19 vaccine. Utilizing our multivariate logistic regression model, we found that prior vaccination, regardless of the number of doses or days since vaccination, was associated with decreased mortality (aOR 0.44, 95% CI: 0.20-0.98) when compared to unvaccinated individuals. Our study showed that COVID-19 related hospitalization after vaccination may occur to a small percentage of patients, mainly those who are partially vaccinated. However, our findings underline that prior vaccination, even when partial, is associated with a decreased risk of death. Ongoing vaccination efforts should remain an absolute priority. |
---|---|
Bibliography: | Informit, Melbourne (Vic) Tropical Medicine and Infectious Disease, Vol. 6, No. 4, Dec 2021, [1]-6 |
ISSN: | 2414-6366 2414-6366 |