Strong Long-Term Survival with Targeted Therapy in Inoperable/Metastatic Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) belong to a group of cancers called soft-tissue sarcomas. Soft-tissue sarcomas develop in the tissues that support and connect the body, including muscles, nerves, tendons and joints. In this paper we report a case of 67-years old man with unresectable GIST an...

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Published inCurrent health sciences journal Vol. 46; no. 3; pp. 315 - 318
Main Authors TUTA, CRISTIAN, VATU, BOGDAN-IONEL, ARTENE, STEFAN-ALEXANDRU
Format Journal Article
LanguageEnglish
Published Medical University Publishing House Craiova 01.01.2020
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Summary:Gastrointestinal stromal tumors (GISTs) belong to a group of cancers called soft-tissue sarcomas. Soft-tissue sarcomas develop in the tissues that support and connect the body, including muscles, nerves, tendons and joints. In this paper we report a case of 67-years old man with unresectable GIST and associated liver metastasis who experienced a very good response to Imatinib mesylate (Glivec®) therapy in first line for over 10 years. Even after progression and discovery of liver metastasis, increasing the Glivec® dose proved to be an efficient strategy with no added toxicity and an overall satisfactory quality of life.
ISSN:2067-0656
2069-4032
DOI:10.12865/CHSJ.46.03.16