Transcriptional Control of Monocyte Development

Monocytes and macrophages are key cells involved in the early progression of atherosclerosis. Transcription factors that control their development in the bone marrow are important therapeutic targets to control the numbers and functions of these cells in disease. This review highlights what is curre...

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Published inArteriosclerosis, thrombosis, and vascular biology Vol. 36; no. 9; pp. 1722 - 1733
Main Authors Zhu, Yanfang Peipei, Thomas, Graham D., Hedrick, Catherine C.
Format Journal Article
LanguageEnglish
Published 07.07.2016
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Summary:Monocytes and macrophages are key cells involved in the early progression of atherosclerosis. Transcription factors that control their development in the bone marrow are important therapeutic targets to control the numbers and functions of these cells in disease. This review highlights what is currently known about the transcription factors that are critical for monocyte development.
ISSN:1079-5642
1524-4636
DOI:10.1161/ATVBAHA.116.304054