Exogenous application of histone demethylase inhibitor trans-2-phenylcyclopropylamine mimics FLD loss-of-function phenotype in terms of systemic acquired resistance in Arabidopsis thaliana
Plants often learn from previous infections to mount higher level of resistance during subsequent infections, a phenomenon referred to as systemic acquired resistance (SAR). During primary infection, mobile signals generated at the infection site subsequently move to the rest of plant to activate SA...
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Published in | Plant signaling & behavior Vol. 9 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Landes Bioscience
15.07.2014
|
Subjects | |
Online Access | Get full text |
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Summary: | Plants often learn from previous infections to mount higher level of resistance during subsequent infections, a phenomenon referred to as systemic acquired resistance (SAR). During primary infection, mobile signals generated at the infection site subsequently move to the rest of plant to activate SAR. SAR activation is associated with alteration in the nucleosomal composition at the promoters of several defense-related genes. However, genetic regulations of such epigenetic modifications are largely obscure. Recently, we have demonstrated that
Reduced Systemic immunity1
/
FLOWERING LOCUS D
(
RSI1
; alias
FLD
) a homolog of human histone demethylase, is required for SAR development in
Arabidopsis
. Here, we report that exogenous application of a histone demethylase inhibitor trans-2-phenylcyclopropylamine (2-PCPA) mimics
rsi1
/
fld
loss-of-function phenotypes in terms of SAR and associated histone demethylation at the promoters of
PR1
,
WRKY 29
, and
WRKY6
genes, and as well as flowering phenotypes. Our results suggest histone demethylase activity of FLD is important for controlling SAR activation. |
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ISSN: | 1559-2316 1559-2324 |
DOI: | 10.4161/psb.29658 |