Variability of Pulse Oximetry Measurement Over One Year in Children with Sickle Cell Disease Depends on Initial Oxygen Saturation Measurement

A prospective cohort of children with sickle cell disease (SCD) was evaluated to determine the variability of daytime pulse oximetry among three measurements over approximately one year. Fifty-eight participants were evaluated. Asymptomatic children with initial oxygen saturation ≤ 92% had a mean ra...

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Published inPediatric blood & cancer Vol. 54; no. 7; pp. 1017 - 1019
Main Authors Mullin, Jonathan E., Cooper, Ben, Seicean, Sinziana, Strunk, Robert, Rosen, Carol, Redline, Susan, Kemp, James, DeBaun, Michael R.
Format Journal Article
LanguageEnglish
Published 01.07.2010
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Summary:A prospective cohort of children with sickle cell disease (SCD) was evaluated to determine the variability of daytime pulse oximetry among three measurements over approximately one year. Fifty-eight participants were evaluated. Asymptomatic children with initial oxygen saturation ≤ 92% had a mean range over one year of 4.6% (2.1% to 7.5%) while clinically stable. In contrast, asymptomatic children whose oxygen saturation was > 92% had a mean range of 1.9% (0 to 5.5%). These results suggest changes in pulse oximetry measurement of 4.6% may not be clinically significant in otherwise healthy children with SCD with previous pulse oximetry ≤ 92%.
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.22420