Lower viral loads in rhinovirus-challenged allergic subjects despite reduced innate immunity

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Bibliographic Details
Published inAnnals of allergy, asthma, & immunology Vol. 128; no. 4; pp. 414 - 422.e2
Main Authors Feng, Xin, Lawrence, Monica G, Payne, Spencer C, Mattos, Jose, Etter, Elaine, Negri, Julie A., Murphy, Deborah, Kennedy, Joshua L, Steinke, John W, Borish, Larry
Format Journal Article
LanguageEnglish
Published 12.01.2022
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ISSN1081-1206
1534-4436
DOI10.1016/j.anai.2022.01.007

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Bibliography:Author contributions: Xin Feng was responsible for helping design and for performing all of the immunofluorescent studies. Monica Lawrence was responsible for overseeing the virology studies including preparing virus for inoculation, performing viral serologies, and associated regulatory requirements including holding the IND for the RV-A16. Spencer Payne and Jose Mattos helped design the nasal pathology studies and were responsible for performing the nasal biopsies. Elaine Etter and Julie Negri were responsible for performing the transcriptomic and proteomic studies. Deborah Murphy performed the clinical trials including subject screening, viral inoculation, assessing clinical outcomes, and performing all the essential regulatory and safety studies. Joshua Kennedy was responsible for performing the nasal viral titer concentration studies. John Steinke directs the transcriptomic and proteomic research laboratory and performed many of these studies. And, finally, Larry Borish was responsible for the overall direction of these studies including design, funding, and primary authorship for manuscripts.
ISSN:1081-1206
1534-4436
DOI:10.1016/j.anai.2022.01.007