Hemorrhage complicating heparin treatment in a patient with myxedema

A 75 year-old woman was admitted for a myxoedematous coma. Treatment included a prophylactic administration of low molecular weight heparin. During recovery from coma she experienced pain in her right calf. The anticoagulant therapy was switched to subcutaneous calcium heparin. However, the latter h...

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Bibliographic Details
Published inAnnales françaises d'anesthésie et de réanimation Vol. 15; no. 2; p. 202
Main Authors Bulckaen, E, Woestelandt, H, Le Borgne, J M, Chanteau, C
Format Journal Article
LanguageFrench
Published France 1996
Subjects
Aged
Blood Coagulation Disorders - etiology
Coma - complications
Female
Hemorrhage - etiology
Heparin, Low-Molecular-Weight - administration & dosage
Heparin, Low-Molecular-Weight - adverse effects
Heparin, Low-Molecular-Weight - blood
Humans
Injections, Subcutaneous
Myxedema - complications
Partial Thromboplastin Time
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Summary:A 75 year-old woman was admitted for a myxoedematous coma. Treatment included a prophylactic administration of low molecular weight heparin. During recovery from coma she experienced pain in her right calf. The anticoagulant therapy was switched to subcutaneous calcium heparin. However, the latter had to be discontinued due to the formation of a haematoma of a thigh. Clinical and biological data were in favour of a mechanism of heparin stocking during coma followed by its release during recovery.
ISSN:0750-7658