The effect of oral rehydration therapy on pancreatic function in patients with acute intestinal infections

• Published in: Žurnal mikrobiologii, ėpidemiologii i immunobiologii no. 1; p. 84
• Main Authors: Burkin, V S, Dubova, A V, Dorofeeva, S D, Bataeva, S E
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.01.1995
• Subjects: Acute Disease; Adolescent; Adult; Blood Glucose - analysis; Dysentery, Bacillary - blood; Dysentery, Bacillary - physiopathology; Dysentery, Bacillary - therapy; Female; Fluid Therapy - methods; Humans; Intestinal Diseases - blood; Intestinal Diseases - physiopathology; Intestinal Diseases - therapy; Male; Pancreas - physiopathology; Pancreatic Hormones - blood; Salmonella Food Poisoning - blood; Salmonella Food Poisoning - physiopathology; Salmonella Food Poisoning - therapy; Vibrio Infections - blood; Vibrio Infections - physiopathology; Vibrio Infections - therapy
• ISSN: 0372-9311

The results of the study of the level of pancreatic hormones (insulin, glucagon, C-peptide and trypsin), carried out with the aim of finding out the character of relationship between hormonal disturbances and the state of carbohydrate metabolism, as well as the influence of oral rehydration therapy (ORT) with glucose-salt solutions on the function of the pancreas, are summarized. All subjects to be examined were divided into two groups receiving different kinds of ORT. The patients in group 1 (153 subjects) were treated with glucosolan and in group 2 (73 subjects), with sodium citrate in an amount of 2.5-5 lit. over the 6-hour period of treatment. The determination of the content of immunoreactive insulin, glucagon C-peptide and trypsin in the blood as the characteristics of the hormonal activity of the pancreas has made it possible to find out disturbances in the incretory and excretory activity of the pancreas in patients with acute enteric infections of different etiology. ORT with glucosolan and sodium citrate facilitates the restoration of pancreatic function in 65-70% of in patients with acute enteric infections of different etiology.