Diagnostic test-system for the immunoenzymatic detection of meningococcal antigen

To detect meningococcal antigen, the use of the enzyme-labeled immunosorbent assay (ELISA), a new variant of the immunoenzymatic method, permitting one to carry out quantitative analysis, is proposed. The optimum conditions for the test to detect group A meningococcal antigen, as well as the procedu...

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Bibliographic Details
Published inŽurnal mikrobiologii, ėpidemiologii i immunobiologii no. 2; p. 70
Main Authors Shabalina, S V, Semina, N A, Rubtsov, I V, Pokrovskaia, N Ia, Ermolin, G A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.02.1983
Subjects
Animals
Antigens, Bacterial - analysis
Enzyme-Linked Immunosorbent Assay
Humans
Meningococcal Infections - diagnosis
Neisseria meningitidis - immunology
Polysaccharides, Bacterial - analysis
Rabbits
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Summary:To detect meningococcal antigen, the use of the enzyme-labeled immunosorbent assay (ELISA), a new variant of the immunoenzymatic method, permitting one to carry out quantitative analysis, is proposed. The optimum conditions for the test to detect group A meningococcal antigen, as well as the procedure for the approbation of the test on patients with meningococcal infection and on healthy persons, have been worked out. The method is shown to be highly specific and sensitive.
ISSN:0372-9311
2686-7613