Endobronchial non-Hodgkin's lymphoma

The authors report a case of endobronchial non-Hodgkin lymphoma, in a 48-year-old woman. This is an exceptional localization. When it reveals the disease, as was the case in the index patient, clinical presentation is usually atelectasis with fever. Diagnosis was established upon bronchoscopy. Histo...

Full description

Saved in:
Bibliographic Details
Published inLa semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris Vol. 60; no. 10; p. 698
Main Authors Loison, F, Patri, B, Vilde, F, Ray, B, Thibier, G, Broussard, O, Dubrisay, J
Format Journal Article
LanguageFrench
Published France 01.03.1984
Subjects
Adolescent
Adult
Aged
Bronchial Neoplasms - immunology
Bronchial Neoplasms - pathology
Bronchial Neoplasms - surgery
Bronchoscopy
Female
Humans
IgA Deficiency
Lymphoma, Non-Hodgkin - immunology
Lymphoma, Non-Hodgkin - pathology
Lymphoma, Non-Hodgkin - surgery
Male
Middle Aged
Pneumonectomy
Pulmonary Atelectasis - etiology
Online AccessGet more information

Cover

More Information
Summary:The authors report a case of endobronchial non-Hodgkin lymphoma, in a 48-year-old woman. This is an exceptional localization. When it reveals the disease, as was the case in the index patient, clinical presentation is usually atelectasis with fever. Diagnosis was established upon bronchoscopy. Histologic examination of biopsy specimens showed an immunoblastic lymphosarcoma. Total pneumonectomy and chemotherapy failed to prevent rapid deterioration with a fatal outcome 7 months after onset. A selective total IgA deficiency and a familial history of malignant tumors were recorded. Immunoblastic sarcoma has a poor prognosis. It often follows a disease whose mechanism is ascribed to an immunological disorder. Lymphoma arising in a patients with prior immune disease should suggest the diagnosis of immunoblastic sarcoma.