Morphea Associated with Adalimumab Treatment: The Role of TNF-α in Inhibition of Fibrosis

Anti-tumor necrosis factor alpha (anti-TNF-α) comprises a group of drugs that inhibit the action of cytokine TNF-α, and are used to treat diseases mainly caused by this cytokine. An increase in cutaneous adverse events has been observed with similar anti-TNF biologic treatments frequently used in cl...

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Bibliographic Details
Published inSkinmed Vol. 22; no. 4; p. 296
Main Authors Gracia-Cazaña, Tamara, Fuentelsaz, Victoria, Navarro-Bielsa, Alba, Giner-Serret, Emilio, García-Latasa, Francisco Javier
Format Journal Article
LanguageEnglish
Published United States 2024
Subjects
Adalimumab - adverse effects
Adalimumab - therapeutic use
Anti-Inflammatory Agents - adverse effects
Anti-Inflammatory Agents - therapeutic use
Fibrosis - chemically induced
Humans
Scleroderma, Localized - chemically induced
Tumor Necrosis Factor-alpha - antagonists & inhibitors
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Summary:Anti-tumor necrosis factor alpha (anti-TNF-α) comprises a group of drugs that inhibit the action of cytokine TNF-α, and are used to treat diseases mainly caused by this cytokine. An increase in cutaneous adverse events has been observed with similar anti-TNF biologic treatments frequently used in clinical practice.
ISSN:1751-7125