Mycoplasma genitalium prevalence, co-infection and macrolide resistance-associated mutations in Southern Vietnam

is an emerging sexually transmitted infection, with increasing rates of macrolide resistance and some ways of treatments being recommended by many countries. This study aimed to investigate the prevalence of infection, co-infection with other sexually transmitted organisms, and the frequency of macr...

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Bibliographic Details
Published inLe infezioni in medicina Vol. 32; no. 2; p. 222
Main Authors Lam, Pham Phuoc Hung, Nguyen, Ngoc Hieu, Nguyen, Thi Thanh Tho, Trinh, Ngo Binh, Luong, Bac An
Format Journal Article
LanguageEnglish
Published Italy 2024
Subjects
Neisseria gonorrhoeae
co-infection
Chlamydia trachomatis
Mycoplasma genitalium
macrolide resistance
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Summary:is an emerging sexually transmitted infection, with increasing rates of macrolide resistance and some ways of treatments being recommended by many countries. This study aimed to investigate the prevalence of infection, co-infection with other sexually transmitted organisms, and the frequency of macrolide antibiotic resistance genotypes identified in urethral specimens collected from male and urethral, vaginal and cervical specimens from female who visited the STIs clinic of HCMC Hospital of Dermato-Venereology, Vietnam. The results obtained positive samples for was 8.46%, was 6.28%, and was 5.95%. Fifty-five out of 90 samples were found to have mutations in the 23S rRNA gene associated with macrolide resistance (61.11%). co-infection was 6.19%, and was 1.22%. The percentage of carrying the macrolide resistance mutant gene co-infected with accounted for 37.50%. The high prevalence of the mutations associated with macrolide resistance showed the importance of testing.
ISSN:2532-8689