A ratiomectic aptasensor with enhanced signals based on peroxidase-like enzymes and NH 2 -MIL-101@MoS 2 for trace detection of deoxynivalenol in traditional Chinese herbs

The accumulation of the deoxynivalenol (DON) in the human body poses a significant health risk that is often overlooked, and we urgently need an ultra-sensitive rapid detection platform. Due to the porosity of NH -MIL-101@MoS , an increased loading of toluidine blue (TB) serves to create a signal re...

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Bibliographic Details
Published inFood chemistry Vol. 441; p. 138381
Main Authors Liu, Yongxin, Lai, Haohong, Ming, Pingtao, Chen, Pengsheng, Wang, Shumei, Zhai, Haiyun
Format Journal Article
LanguageEnglish
Published England 30.05.2024
Subjects
Electrochemical detection
Metal organic frameworks
Dual signal
Peroxidase-like enzymes
Traditional Chinese herbs
Aptasensor
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Summary:The accumulation of the deoxynivalenol (DON) in the human body poses a significant health risk that is often overlooked, and we urgently need an ultra-sensitive rapid detection platform. Due to the porosity of NH -MIL-101@MoS , an increased loading of toluidine blue (TB) serves to create a signal reference. Cobalt@carbon (CoC) derived from metal organic frameworks was combined with NH -MIL-101(NH -MIL-101@CoC) to form an enzyme-free Nanoprobe (Apt-pro) with significant catalytic properties. The ratio (I /I ) was changed by varying the electrochemical signal of benzoquinone (BQ) (I ) and the amount of TB deposition (I ). This aptasensor was successfully applied to detect DON in malt and peach seed, which exhibited a great linear range from 1 fg/mL to 10 ng/mL and low detection limit of 0.31 fg/mL for DON.
ISSN:1873-7072