A ratiomectic aptasensor with enhanced signals based on peroxidase-like enzymes and NH 2 -MIL-101@MoS 2 for trace detection of deoxynivalenol in traditional Chinese herbs

The accumulation of the deoxynivalenol (DON) in the human body poses a significant health risk that is often overlooked, and we urgently need an ultra-sensitive rapid detection platform. Due to the porosity of NH -MIL-101@MoS , an increased loading of toluidine blue (TB) serves to create a signal re...

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Bibliographic Details
Published inFood chemistry Vol. 441; p. 138381
Main Authors Liu, Yongxin, Lai, Haohong, Ming, Pingtao, Chen, Pengsheng, Wang, Shumei, Zhai, Haiyun
Format Journal Article
LanguageEnglish
Published England 30.05.2024
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Summary:The accumulation of the deoxynivalenol (DON) in the human body poses a significant health risk that is often overlooked, and we urgently need an ultra-sensitive rapid detection platform. Due to the porosity of NH -MIL-101@MoS , an increased loading of toluidine blue (TB) serves to create a signal reference. Cobalt@carbon (CoC) derived from metal organic frameworks was combined with NH -MIL-101(NH -MIL-101@CoC) to form an enzyme-free Nanoprobe (Apt-pro) with significant catalytic properties. The ratio (I /I ) was changed by varying the electrochemical signal of benzoquinone (BQ) (I ) and the amount of TB deposition (I ). This aptasensor was successfully applied to detect DON in malt and peach seed, which exhibited a great linear range from 1 fg/mL to 10 ng/mL and low detection limit of 0.31 fg/mL for DON.
ISSN:1873-7072