H 2 S serves as the immunoregulatory essence of apoptotic cell death
Apoptosis supports tissue homeostasis and prevents immune disorders by removing damaged and functionally aberrant cells. Here, Ou et al. utilized genetic, pharmacological, and proteomic approaches focused on sulfur amino acid catabolism to discover that hydrogen sulfide (H S) release during apoptosi...
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Published in | Cell metabolism Vol. 36; no. 1; p. 3 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
02.01.2024
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Abstract | Apoptosis supports tissue homeostasis and prevents immune disorders by removing damaged and functionally aberrant cells. Here, Ou et al. utilized genetic, pharmacological, and proteomic approaches focused on sulfur amino acid catabolism to discover that hydrogen sulfide (H
S) release during apoptosis suppresses Th17 cell differentiation, thus providing therapeutic targets for autoimmune diseases. |
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AbstractList | Apoptosis supports tissue homeostasis and prevents immune disorders by removing damaged and functionally aberrant cells. Here, Ou et al. utilized genetic, pharmacological, and proteomic approaches focused on sulfur amino acid catabolism to discover that hydrogen sulfide (H
S) release during apoptosis suppresses Th17 cell differentiation, thus providing therapeutic targets for autoimmune diseases. |
Author | Cáliz-Molina, María Ángeles Hine, Christopher Martín-Montalvo, Alejandro Ponti, András K |
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SubjectTerms | Apoptosis Homeostasis Hydrogen Sulfide - metabolism Hydrogen Sulfide - pharmacology Proteomics |
Title | H 2 S serves as the immunoregulatory essence of apoptotic cell death |
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