1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry: A Recent Overview

The thiazole ring is a unique heterocyclic motif among heterocyclic compounds. This five-member ring with one nitrogen and one sulphur atom displays a wide array of pharmacological activities, including anti-inflammatory, antimicrobial, anticancer, antidiabetic, antiviral, etc., by acting on several...

Full description

Saved in:
Bibliographic Details
Published inAnti-inflammatory & anti-allergy agents in medicinal chemistry Vol. 22; no. 3; p. 133
Main Authors Kushwaha, Pragati, Pandey, Shashi
Format Journal Article
LanguageEnglish
Published United Arab Emirates 2023
Subjects
biological activities
antiviral
anti-inflammatory
antibacterial
Thiazole
anticancer
Online AccessGet more information

Cover

More Information
Summary:The thiazole ring is a unique heterocyclic motif among heterocyclic compounds. This five-member ring with one nitrogen and one sulphur atom displays a wide array of pharmacological activities, including anti-inflammatory, antimicrobial, anticancer, antidiabetic, antiviral, etc., by acting on several targets. Its broad range of medical applications has inspired us to study this opulent heterocyclic molecule. The current review summarizes synthetic approaches for the preparation of thiazole derivatives in brief and discusses the promising biological activities of this scaffold. This review will be useful to the drug discovery community and will facilitate the synthesis and development of novel and potent thiazole derivatives, which may serve as lead molecules for the treatment of various diseases.
ISSN:1875-614X