Use of Cryoprecipitate in Newborn Infants

Cryoprecipitate is a transfusion blood product derived from fresh-frozen plasma (FFP), comprised mainly of the insoluble precipitate that gravitates to the bottom of the container when plasma is thawed and refrozen. It is highly enriched in coagulation factors I (fibrinogen), VIII, and XIII; von Wil...

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Bibliographic Details
Published inNewborn (Clarksville, Md.) Vol. 2; no. 1; p. 11
Main Authors Tyagi, Manvi, Guaragni, Brunetta, Dendi, Alvaro, Tekleab, Atnafu Mekonnen, Motta, Mario, Maheshwari, Akhil
Format Journal Article
LanguageEnglish
Published United States 01.01.2023
Subjects
Cryoprecipitated antihemophilic factor
Transfusion product
Newborn neonate infant
Factor VIII
Fibrinogen
Cryoprecipitate
Factor I
Factor XII
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Summary:Cryoprecipitate is a transfusion blood product derived from fresh-frozen plasma (FFP), comprised mainly of the insoluble precipitate that gravitates to the bottom of the container when plasma is thawed and refrozen. It is highly enriched in coagulation factors I (fibrinogen), VIII, and XIII; von Willebrand factor (vWF); and fibronectin. In this article, we have reviewed currently available information on the preparation, properties, and clinical importance of cryoprecipitate in treating critically ill neonates. We have searched extensively in the databases PubMed, Embase, and Scopus after short-listing keywords to describe the current relevance of cryoprecipitate.
ISSN:2769-514X