Therapeutic strategies for upper aerodigestive tract cancers

Upper aerodigestive tract squamous cell carcinomas are the most frequent head and neck cancers. They are generally associated with alcohol and tobacco, but can also be HPV-induced for the oropharynx. Their diagnosis is often late and at a locally advanced stage, making treatment more complex. After...

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Bibliographic Details
Published inLa Revue du praticien Vol. 72; no. 10; p. 1086
Main Authors Fanchette, Julia, Halimi, Caroline
Format Magazine Article
LanguageFrench
Published France 01.12.2022
Subjects
Carcinoma, Squamous Cell
Combined Modality Therapy
Head and Neck Neoplasms - diagnosis
Head and Neck Neoplasms - therapy
Humans
Neoplasm Recurrence, Local
Head and Neck Neoplasms
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Summary:Upper aerodigestive tract squamous cell carcinomas are the most frequent head and neck cancers. They are generally associated with alcohol and tobacco, but can also be HPV-induced for the oropharynx. Their diagnosis is often late and at a locally advanced stage, making treatment more complex. After a complete primary assessment, the most suitable therapeutic sequence is proposed to the patient after a case-by-case discussion in a multidisciplinary meeting. The therapeutic arsenal for head and neck cancers is mainly composed of surgery, radiotherapy, chemotherapy, and recently immunotherapy. The latter renewed the management of patients with unresectable locoregional recurrence or metastatic.
ISSN:2101-017X