Research advances of adipose stem cell matrix gel in promoting wound healing

In recent years, with the problem of aging population in China being prominant, the number of patients with chronic wounds such as diabetic foot, pressure ulcer, and vascular ulcer is increasing. Those diseases seriously affect the life quality of patients and increase the economy and care burden of...

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Bibliographic Details
Published inZhonghua shao shang yu chuang mian xiu fu za zhi Vol. 39; no. 1; p. 81
Main Authors Xing, N, Huo, R, Wang, H T, Yang, J C, Chen, J, Peng, L, Liu, X W
Format Journal Article
LanguageChinese
Published China 20.01.2023
Subjects
Adipocytes
Adipose Tissue
Aged
Extracellular Matrix
Humans
Stem Cells
Wound Healing - physiology
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Summary:In recent years, with the problem of aging population in China being prominant, the number of patients with chronic wounds such as diabetic foot, pressure ulcer, and vascular ulcer is increasing. Those diseases seriously affect the life quality of patients and increase the economy and care burden of the patients' family, which have been one of the most urgent clinical problems. Many researches have confirmed that adipose stem cells can effectively promote wound healing, while exogenous protease is needed, and there are ethical and many other problems, which limit the clinical application of adipose stem cells. Adipose stem cell matrix gel is a gel-like mixture of biologically active extracellular matrix and stromal vascular fragment obtained from adipose tissue by the principle of fluid whirlpool and flocculation precipitation. It contains rich adipose stem cells, hematopoietic stem cells, endothelial progenitor cells, and macrophages, etc. The preparation method of adipose stem cell matrix gel is simple and
ISSN:2097-1109