Current State of 44 Ti/ 44 Sc Radionuclide Generator Systems and Separation Chemistry

• Published in: Current radiopharmaceuticals Vol. 16; no. 2; p. 95
• Main Authors: Schmidt, Christine E, Gajecki, Leah, Deri, Melissa A, Sanders, Vanessa A
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2023
• Subjects: Positron-Emission Tomography - methods; Radioisotopes; Radionuclide Generators; Radiopharmaceuticals; Scandium; Titanium; diagnostics; radioisotope production; titanium; Scandium; generators; radiolabeling; PET

In recent years, there has been an increased interest in Ti/ Sc generators as an onsite source of Sc for medical applications without needing a proximal cyclotron. The relatively short half-life (3.97 hours) and high positron branching ratio (94.3%) of Sc make it a viable candidate for positron emis...