Acne and diet: a review of pathogenic mechanisms

Acne is a chronic inflammatory disease of the pilosebaceous unit with multifactorial etiology. Abnormal proliferation of keratinocytes, altered sebum production, inflammation of the sebaceous follicle, and colonization by Cutibacterium acnes have been traditionally implicated. However, the diet has...

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Bibliographic Details
Published inBoletin medico del Hospital Infantil de Mexico Vol. 79; no. 2; p. 83
Main Authors González-Mondragón, Edgar A, Ganoza-Granados, Luciana Del C, Toledo-Bahena, Mirna Eréndira, Valencia-Herrera, Adriana M, Duarte-Abdala, Mario R, Camargo-Sánchez, Karen A, Mena-Cedillos, Carlos A
Format Journal Article
LanguageEnglish
Published Mexico 2022
Subjects
Acne Vulgaris - microbiology
Acne Vulgaris - pathology
Diet
Humans
Inflammation - complications
Propionibacterium acnes - physiology
Sebum
Acne vulgaris
Dieta
Diet
Índice glicémico
Acné vulgar
Carga glicémica
Glycemic index
Glycemic load
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Summary:Acne is a chronic inflammatory disease of the pilosebaceous unit with multifactorial etiology. Abnormal proliferation of keratinocytes, altered sebum production, inflammation of the sebaceous follicle, and colonization by Cutibacterium acnes have been traditionally implicated. However, the diet has also been highlighted in the pathogenesis because of its direct relation with some biochemical markers and the transcription of specific genes associated with sebaceous gland activity, inflammation, and bacterial proliferation, which together promote the development of the disease, affect the severity of the condition, and modify its response to treatment.
ISSN:1665-1146