Brain plasticity after rehabilitation in a severe case of artery of Percheron stroke assessed with multimodal MR imaging

Artery of Percheron (AOP) stroke is a rare event. We describe an AOP stroke involving both thalami and the midbrain, resulting in a multifunctional clinical impairment. Intensive inpatient multidisciplinary rehabilitation favored the recovery of motor deficits, together with the improvement of cogni...

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Published inNeurocase p. 1
Main Authors Tavazzi, E, Bergsland, N, Pirastru, A, Pelizzari, L, Cazzoli, M, Saibene, F L, Navarro, J S, Farina, E, Comanducci, A, Cecconi, P, Baglio, F
Format Journal Article
LanguageEnglish
Published England 24.04.2022
Subjects
fMRI
MRI
stroke
neurorehabilitation
Artery of percheron
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Summary:Artery of Percheron (AOP) stroke is a rare event. We describe an AOP stroke involving both thalami and the midbrain, resulting in a multifunctional clinical impairment. Intensive inpatient multidisciplinary rehabilitation favored the recovery of motor deficits, together with the improvement of cognitive dysfunctions. MRI assessment in the chronic post-stroke phase showed structural and functional reorganization in response to the extended thalamic tissue damage and absence of revascularization. Thalamo-cortical networks involving frontal and prefrontal regions, as well as parietal areas were disrupted, whereas increased functional thalamo-occipital connectivity was found. This report sheds light on brain reorganization following AOP stroke after rehabilitation..
ISSN:1465-3656